SenexFOXO4-DRI
Clear the cells that should have died.
About
What it is
FOXO4-DRI is a senolytic peptide — it selectively triggers apoptosis in senescent cells, the damaged cells that refuse to die and instead secrete inflammatory signals that age surrounding tissue. Clear them out and let healthy cells take over.
How it works
FOXO4-DRI is a retro-inverso peptide that disrupts the FOXO4-p53 interaction in senescent cells. Normally, FOXO4 keeps p53 sequestered, preventing senescent cells from undergoing apoptosis. FOXO4-DRI frees p53, allowing it to trigger programmed cell death in these damaged cells.
Benefits
Who it's for
What to expect
Days 1–3
Senolytic cycle administered. Senescent cell clearance begins.
Week 2–4
Post-cycle recovery. Healthy cells fill cleared niches.
Next cycle
Repeated cycles clear additional senescent cells. Benefits accumulate.
Safety & tolerability
FOXO4-DRI is a targeted senolytic — it selectively affects senescent cells, not healthy ones. It's typically used in short cycles (a few days) rather than continuously. Our care team designs your cycling protocol and monitors inflammatory markers.
How we compound
Single-source API
Every peptide is sourced from one vetted pharmaceutical-grade supplier — no blending from multiple sources.
Third-party tested
Independent labs verify purity, potency, sterility, and endotoxin levels before any batch is released.
Care team reviewed
A real person reviews your profile, your protocol, and your progress. Not an algorithm.
Longevity
SenexFOXO4-DRI
Every protocol is reviewed by our care team before it ships. Questions? Learn more
$349/mo
