Protocols/Spark
Hormonal Health

SparkKisspeptin-10

Upstream hormone signaling. Where it all starts.

$139/month
HSA/FSA eligible Ships free Cancel anytime
Kisspeptin-10

About

What it is

Kisspeptin sits upstream of GnRH in the hormonal cascade — it's the signal that tells your hypothalamus to release GnRH, which then triggers LH and FSH. Supporting kisspeptin means supporting the entire chain from the top.

How it works

Kisspeptin binds to GPR54 receptors on GnRH neurons in the hypothalamus, triggering GnRH release. It sits at the very top of the reproductive hormone cascade — upstream of GnRH, which is upstream of LH and FSH, which drive testosterone and sperm production.

Benefits

Stimulates GnRH release from the hypothalamus
Supports the entire reproductive hormone cascade
May improve testosterone and fertility
Works at the top of the hormonal chain

Who it's for

Upstream hormonal optimization
Those who want to support natural GnRH production
Fertility and reproductive health
Research-oriented hormone protocols

What to expect

Week 1

GnRH pulses increase. Downstream hormone cascade activates.

Week 2–4

LH, FSH, and testosterone begin rising.

Week 4–8

Full hormonal cascade optimization. Fertility markers improve.

Safety & tolerability

Kisspeptin is a naturally occurring neuropeptide that's part of normal puberty initiation and reproductive function. It's being actively studied for fertility applications. Our care team evaluates your hormonal profile and monitors your response.

How we compound

Single-source API

Every peptide is sourced from one vetted pharmaceutical-grade supplier — no blending from multiple sources.

Third-party tested

Independent labs verify purity, potency, sterility, and endotoxin levels before any batch is released.

Care team reviewed

A real person reviews your profile, your protocol, and your progress. Not an algorithm.

Share this protocol

$139/mo