The Endurance Stack
Exercise physiology in three peptides.
$477/mo
$409/mo
Save $68/mo vs. buying individually
3 protocols included
How This Stack Works
AICAR converts to ZMP, mimicking AMP and activating AMPK — triggering fatty acid oxidation, glucose uptake, and mitochondrial biogenesis. SLU-PP-332 activates ERR transcription factors, upregulating oxidative metabolism genes and shifting muscle fiber types toward slow-twitch endurance fibers. MOTS-C activates AMPK through a complementary mitochondrial pathway, enhancing metabolic homeostasis and improving insulin sensitivity in muscle tissue.
Why This Combination
Endurance isn't just cardiovascular fitness — it's cellular energy production. AICAR activates AMPK, the master energy sensor that triggers the same metabolic cascade as prolonged exercise: increased fatty acid oxidation, enhanced glucose uptake, and mitochondrial biogenesis. SLU-PP-332 activates ERR (estrogen-related receptor) pathways, shifting muscle fiber composition toward fatigue-resistant types and increasing mitochondrial content. MOTS-C, a mitochondrial-derived peptide, fine-tunes the metabolic machinery — improving how efficiently each mitochondrion converts fuel to ATP. Together, you're building more mitochondria, making each one more efficient, and running all the metabolic pathways that exercise would activate.
Ideal For
Endurance athletes
Metabolic conditioning
Those with limited training time
Complementing cardio and endurance programs
What to Expect
Week 1–2
Metabolism
AMPK activation begins. Fat oxidation increases. Metabolic substrate use shifts.
Week 3–4
Adaptation
Mitochondrial biogenesis in muscle tissue. Exercise tolerance improves.
Week 6–8
Performance
Endurance capacity measurably increases. Fatigue resistance improves.
Week 10–12
Optimization
Full metabolic conditioning. Muscle fiber composition shifting. Peak endurance.
Ready to start?
The Endurance Stack — $409/mo. Save $68 vs. buying separately. Care team reviewed. Ships free.
HSA/FSA eligible · Cancel anytime · Ships in 3-5 days